three vector crispr sam system Search Results


vp64 activation domain  (OriGene)
86
OriGene vp64 activation domain
Vp64 Activation Domain, supplied by OriGene, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/vp64 activation domain/product/OriGene
Average 86 stars, based on 1 article reviews
vp64 activation domain - by Bioz Stars, 2026-03
86/100 stars
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crispr-pool™sam-human-dual vector  (Shanghai Genechem Ltd)
90
Shanghai Genechem Ltd crispr-pool™sam-human-dual vector
MTX1 was identified as a sorafenib resistance factor by Genome-Scale CRISPRa Screening. (A) Flow chart of <t>CRISPR-Pool™SAM</t> human library screening for genes involving in sorafenib resistance in HCC-LM3 cells. (B) Scatterplot displayed enrichment of sgRNAs in surviving cells after sorafenib treatment compared to the control group. (C) Expression boxplot of LENEP, BCL11B, BAG3, RANBP1, and MTX1 in human HCC patients from GEPIA online database ( http://gepia.cancer-pku.cn/ ). Red boxes indicate tumor tissue and gray boxes represent normal tissue. (D) Kaplan-Meier survival curves were analyzed for above candidate genes based on UALCAN ( http://ualcan.path.uab.edu/analysis.html ). (E) The mRNA expression level of MTX1 in 40 pairs of HCC and adjacent normal samples were determined by qRT-PCR. The data of qRT-PCR are presented as mean ± SD from three experiments, **P < 0.01.
Crispr Pool™Sam Human Dual Vector, supplied by Shanghai Genechem Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/crispr-pool™sam-human-dual vector/product/Shanghai Genechem Ltd
Average 90 stars, based on 1 article reviews
crispr-pool™sam-human-dual vector - by Bioz Stars, 2026-03
90/100 stars
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crispr-pool™ sam vector  (Genechem)
90
Genechem crispr-pool™ sam vector
MTX1 was identified as a sorafenib resistance factor by Genome-Scale CRISPRa Screening. (A) Flow chart of <t>CRISPR-Pool™SAM</t> human library screening for genes involving in sorafenib resistance in HCC-LM3 cells. (B) Scatterplot displayed enrichment of sgRNAs in surviving cells after sorafenib treatment compared to the control group. (C) Expression boxplot of LENEP, BCL11B, BAG3, RANBP1, and MTX1 in human HCC patients from GEPIA online database ( http://gepia.cancer-pku.cn/ ). Red boxes indicate tumor tissue and gray boxes represent normal tissue. (D) Kaplan-Meier survival curves were analyzed for above candidate genes based on UALCAN ( http://ualcan.path.uab.edu/analysis.html ). (E) The mRNA expression level of MTX1 in 40 pairs of HCC and adjacent normal samples were determined by qRT-PCR. The data of qRT-PCR are presented as mean ± SD from three experiments, **P < 0.01.
Crispr Pool™ Sam Vector, supplied by Genechem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/crispr-pool™ sam vector/product/Genechem
Average 90 stars, based on 1 article reviews
crispr-pool™ sam vector - by Bioz Stars, 2026-03
90/100 stars
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crispr-pool™ sam-human-dual vector lentivirus  (Shanghai Genechem Ltd)
90
Shanghai Genechem Ltd crispr-pool™ sam-human-dual vector lentivirus
MTX1 was identified as a sorafenib resistance factor by Genome-Scale CRISPRa Screening. (A) Flow chart of <t>CRISPR-Pool™SAM</t> human library screening for genes involving in sorafenib resistance in HCC-LM3 cells. (B) Scatterplot displayed enrichment of sgRNAs in surviving cells after sorafenib treatment compared to the control group. (C) Expression boxplot of LENEP, BCL11B, BAG3, RANBP1, and MTX1 in human HCC patients from GEPIA online database ( http://gepia.cancer-pku.cn/ ). Red boxes indicate tumor tissue and gray boxes represent normal tissue. (D) Kaplan-Meier survival curves were analyzed for above candidate genes based on UALCAN ( http://ualcan.path.uab.edu/analysis.html ). (E) The mRNA expression level of MTX1 in 40 pairs of HCC and adjacent normal samples were determined by qRT-PCR. The data of qRT-PCR are presented as mean ± SD from three experiments, **P < 0.01.
Crispr Pool™ Sam Human Dual Vector Lentivirus, supplied by Shanghai Genechem Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/crispr-pool™ sam-human-dual vector lentivirus/product/Shanghai Genechem Ltd
Average 90 stars, based on 1 article reviews
crispr-pool™ sam-human-dual vector lentivirus - by Bioz Stars, 2026-03
90/100 stars
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Image Search Results


MTX1 was identified as a sorafenib resistance factor by Genome-Scale CRISPRa Screening. (A) Flow chart of CRISPR-Pool™SAM human library screening for genes involving in sorafenib resistance in HCC-LM3 cells. (B) Scatterplot displayed enrichment of sgRNAs in surviving cells after sorafenib treatment compared to the control group. (C) Expression boxplot of LENEP, BCL11B, BAG3, RANBP1, and MTX1 in human HCC patients from GEPIA online database ( http://gepia.cancer-pku.cn/ ). Red boxes indicate tumor tissue and gray boxes represent normal tissue. (D) Kaplan-Meier survival curves were analyzed for above candidate genes based on UALCAN ( http://ualcan.path.uab.edu/analysis.html ). (E) The mRNA expression level of MTX1 in 40 pairs of HCC and adjacent normal samples were determined by qRT-PCR. The data of qRT-PCR are presented as mean ± SD from three experiments, **P < 0.01.

Journal: International Journal of Biological Sciences

Article Title: Genome-scale CRISPRa screening identifies MTX1 as a contributor for sorafenib resistance in hepatocellular carcinoma by augmenting autophagy

doi: 10.7150/ijbs.62393

Figure Lengend Snippet: MTX1 was identified as a sorafenib resistance factor by Genome-Scale CRISPRa Screening. (A) Flow chart of CRISPR-Pool™SAM human library screening for genes involving in sorafenib resistance in HCC-LM3 cells. (B) Scatterplot displayed enrichment of sgRNAs in surviving cells after sorafenib treatment compared to the control group. (C) Expression boxplot of LENEP, BCL11B, BAG3, RANBP1, and MTX1 in human HCC patients from GEPIA online database ( http://gepia.cancer-pku.cn/ ). Red boxes indicate tumor tissue and gray boxes represent normal tissue. (D) Kaplan-Meier survival curves were analyzed for above candidate genes based on UALCAN ( http://ualcan.path.uab.edu/analysis.html ). (E) The mRNA expression level of MTX1 in 40 pairs of HCC and adjacent normal samples were determined by qRT-PCR. The data of qRT-PCR are presented as mean ± SD from three experiments, **P < 0.01.

Article Snippet: CRISPR-Pool™SAM-Human-Dual vector was purchased from Shanghai Genechem Co., Ltd (Shanghai, China).

Techniques: CRISPR, Library Screening, Expressing, Quantitative RT-PCR